23:00 | Atlético Goianiense | Home win (outsider), market odds: 4.58 | Atlético Goianiense vs Atlético Mineiro: 0FTFinished2HT 0–1 | Away win (favourite), market odds: 1.88 |  Atlético Mineiroposition 7 | WLD | |
23:00 | position 7Puntarenas | Home win (outsider), market odds: 3.02 | Puntarenas vs Deportivo Saprissa: 0FTFinished1HT 0–1 | Away win (favourite), market odds: 2.22 |  Deportivo Saprissaposition 1 | DLWW | |
23:00 | position 6Alianza | Home win (favourite), market odds: 2.15 | Alianza vs Herrera: 1FTFinished1HT 0–0 | Away win (outsider), market odds: 3.64 |  Herreraposition 5 | WD | |
23:00 | Colón | Home win (outsider), market odds: 3.04 | Colón vs Boca Juniors: 1FTFinished2HT 1–1 | Away win (favourite), market odds: 2.63 |  Boca Juniorsposition 5 | LW | |
23:00 | Mineros de Guayana | Home win (outsider), market odds: 2.68 | Mineros de Guayana vs Carabobo: 2FTFinished3HT 0–1 | Away win (favourite), market odds: 2.59 |  Caraboboposition 1 | D— | |
23:00 | position 1Gotham FC | Home win (outsider), market odds: 3.40 | Gotham FC vs North Carolina Courage: 0FTFinished1HT 0–0 | Away win (favourite), market odds: 2.05 |  North Carolina Courageposition 9 | LL | |
23:00 | Cúcuta Deportivo | Home win (favourite), market odds: 1.61 | Cúcuta Deportivo vs Orsomarso: 3FTFinished0HT 1–0 | Away win (outsider), market odds: 6.10 |  Orsomarsoposition 13 | WL | |
23:00 | San Pedro | —No pre-match price | San Pedro vs Puerto San José: 4FTFinished0 | —No pre-match price |  Puerto San José | DW | |
23:00 | Atlético Pantoja | Home win (favourite), market odds: 2.00 | Atlético Pantoja vs Vega Real: 1FTFinished0HT 1–0 | Away win (outsider), market odds: 3.30 |  Vega Realposition 3 | LW | |
23:00 | position 7Olancho | —No pre-match price | Olancho vs Real España: 3FTFinished1HT 2–0 | —No pre-match price |  Real Españaposition 2 | WLLW | |
23:00 | Limón | Home win (outsider), market odds: 3.09 | Limón vs Aserrí: 4FTFinished2HT 2–1 | Away win (favourite), market odds: 2.14 |  Aserríposition 3 | WW | |
23:00 | Real de Arteaga | Home win (outsider), market odds: 4.50 | Real de Arteaga vs Inter Playa del Carmen: 0FTFinished1 | Away win (favourite), market odds: 1.60 |  Inter Playa del Carmen | W— | |
23:00 | Atlético La Cruz | Home win (favourite), market odds: 2.20 | Atlético La Cruz vs Rayo Zuliano: 2FTFinished0HT 0–0 | Away win (outsider), market odds: 3.00 |  Rayo Zuliano | WD | |
23:00 | Juventus Managua | —No pre-match price | Juventus Managua vs Sport Sébaco: 1FTFinished1HT 1–0 | —No pre-match price |  Sport Sébacoposition 6 | DL | |
| 23:00 | position 10Matagalpa | —No pre-match price | Matagalpa vs Diriangén: 2FTFinished3HT 1–1 | —No pre-match price |  Diriangénposition 2 | LLL | |
23:00 | Municipal Jalapa U20 | —No pre-match price | Municipal Jalapa U20 vs Real Estelí U20: 0FTFinished1HT 0–1 | —No pre-match price |  Real Estelí U20 | WDW | |
23:05 | Unión Magdalena | Home win (outsider), market odds: 4.36 | Unión Magdalena vs Junior: 2FTFinished1HT 0–0 | Away win (favourite), market odds: 1.98 |  Juniorposition 14 | DW | |
23:15 | Alianza Beni | —No pre-match price | Alianza Beni vs Deportivo Cervecería: 1FTFinished1 | —No pre-match price |  Deportivo Cervecería | D— | |
23:30 | position 7Portland Timbers | Home win (favourite), market odds: 2.19 | Portland Timbers vs Atlanta United: 2FTFinished1HT 1–0 | Away win (outsider), market odds: 2.97 |  Atlanta Unitedposition 13 | WWLW | |
23:30 | position 2Cerro Largo | Home win (outsider), market odds: 2.97 | Cerro Largo vs Boston River: 1FTFinished1HT 1–0 | Away win (favourite), market odds: 2.75 |  Boston Riverposition 8 | L— | |
23:30 | position 4LDU Quito | Home win (favourite), market odds: 1.35 | LDU Quito vs Orense: 1FTFinished2HT 0–2 | Away win (outsider), market odds: 9.66 |  Orenseposition 13 | DL | |
| 23:30 | position 3Marathón | Home win (favourite), market odds: 1.33 | Marathón vs UPNFM: 1FTFinished1HT 0–0 | Away win (outsider), market odds: 7.27 |  UPNFMposition 6 | DLLL | |
| 23:45 | Juventud Pinulteca | —No pre-match price | Juventud Pinulteca vs Deportivo Sanarate: 2FTFinished0 | —No pre-match price |  Deportivo Sanarate | LD | |
