23:00 | position 5Sporting San Miguelito | Home win (favourite), market odds: 1.17 | Sporting San Miguelito vs Veraguas United: 3FTFinished2HT 3–1 | Away win (outsider), market odds: 11.87 |  Veraguas Unitedposition 2 | |
23:00 | position 11Racing Club | Home win (favourite), market odds: 2.08 | Racing Club vs Argentinos Juniors: 1FTFinished0HT 0–0 | Away win (outsider), market odds: 4.06 |  Argentinos Juniorsposition 5 | |
23:00 | position 7Defensor Sporting | Home win (favourite), market odds: 1.97 | Defensor Sporting vs Wanderers: 1FTFinished0HT 1–0 | Away win (outsider), market odds: 4.04 |  Wanderersposition 1 | |
23:00 | position 8Pacific | Home win (favourite), market odds: 1.78 | Pacific vs York United: 1FTFinished3HT 1–0 | Away win (outsider), market odds: 4.26 |  York Unitedposition 6 | |
23:00 | position 4Monagas | Home win (favourite), market odds: 1.80 | Monagas vs Deportivo Lara: 0FTFinished1HT 0–0 | Away win (outsider), market odds: 4.16 |  Deportivo Lara | |
23:00 | Municipal | Home win (favourite), market odds: 1.63 | Municipal vs Xelajú: 1FTFinished1HT 0–0 | Away win (outsider), market odds: 5.78 |  Xelajú | |
23:00 | Ciervos | —No pre-match price | Ciervos vs Thó Mayas: 0FTFinished1 | —No pre-match price |  Thó Mayas | |
23:00 | San José FC | Home win (favourite), market odds: 2.19 | San José FC vs Consultants Moravia: 2FTFinished1HT 2–1 | Away win (outsider), market odds: 2.93 |  Consultants Moraviaposition 6 | |
23:00 | Colombia | —No pre-match price | Colombia vs Costa Rica: 1FTFinished0HT 0–0 | —No pre-match price |  Costa Rica | |
23:00 | UA Zacatecas | Home win (favourite), market odds: 2.30 | UA Zacatecas vs Tecos: 3FTFinished0HT 1–0 | Away win (outsider), market odds: 2.80 |  Tecos | |
| 23:00 | Halcones de Zapopan | —No pre-match price | Halcones de Zapopan vs Leones Negros II: 1FTFinished1HT 0–0 | —No pre-match price |  Leones Negros II | |
| 23:00 | Deportiva Venados | —No pre-match price | Deportiva Venados vs Escorpiones: 0FTFinished2 | —No pre-match price |  Escorpiones | |
| 23:00 | Deportivo Dongu | Home win , market odds: 2.50 | Deportivo Dongu vs Sporting Canamy: 1FTFinished2HT 0–1 | Away win , market odds: 2.50 |  Sporting Canamy | |
23:00 | Deportivo Ocotal U20 | —No pre-match price | Deportivo Ocotal U20 vs Managua U20: 0FTFinished1HT 0–1 | —No pre-match price |  Managua U20 | |
23:05 | position 4Atlético Bucaramanga | Home win (favourite), market odds: 2.44 | Atlético Bucaramanga vs Alianza Petrolera: 3FTFinished1HT 0–0 | Away win (outsider), market odds: 3.35 |  Alianza Petroleraposition 16 | |
23:30 | position 7Columbus Crew | Home win (favourite), market odds: 1.92 | Columbus Crew vs Chicago Fire: 0FTFinished0HT 0–0 | Away win (outsider), market odds: 4.05 |  Chicago Fireposition 4 | |
23:30 | position 8Guayaquil City | Home win (outsider), market odds: 3.60 | Guayaquil City vs 9 de Octubre: 1FTFinished1HT 1–0 | Away win (favourite), market odds: 2.07 |  9 de Octubre | |
| 23:30 | Cobán Imperial | Home win (favourite), market odds: 1.39 | Cobán Imperial vs Mixco: 0FTFinished0HT 0–0 | Away win (outsider), market odds: 7.40 |  Mixco | |
