23:00 | position 14Austin | Home win (favourite), market odds: 1.63 | Austin vs Colorado Rapids: 1FTFinished1HT 0–0 | Away win (outsider), market odds: 4.92 |  Colorado Rapidsposition 12 | |
| 23:00 | position 2Dallas | Home win (favourite), market odds: 1.93 | Dallas vs Sporting KC: 2FTFinished1HT 1–0 | Away win (outsider), market odds: 3.94 |  Sporting KCposition 15 | |
| 23:00 | position 5Houston Dynamo | Home win (outsider), market odds: 3.54 | Houston Dynamo vs LA Galaxy: 1FTFinished3HT 1–2 | Away win (favourite), market odds: 1.93 |  LA Galaxyposition 11 | |
| 23:00 | position 6Los Angeles | Home win (favourite), market odds: 1.76 | Los Angeles vs Nashville SC: 0FTFinished1HT 0–0 | Away win (outsider), market odds: 4.17 |  Nashville SCposition 1 | |
| 23:00 | position 10Minnesota United | Home win (favourite), market odds: 1.79 | Minnesota United vs Vancouver Whitecaps: 2FTFinished0HT 1–0 | Away win (outsider), market odds: 4.12 |  Vancouver Whitecapsposition 1 | |
| 23:00 | position 9Real Salt Lake | Home win (favourite), market odds: 1.86 | Real Salt Lake vs Portland Timbers: 3FTFinished1HT 1–0 | Away win (outsider), market odds: 3.98 |  Portland Timbersposition 7 | |
| 23:00 | position 8Seattle Sounders | Home win (favourite), market odds: 1.66 | Seattle Sounders vs SJ Earthquakes: 2FTFinished2HT 1–1 | Away win (outsider), market odds: 4.70 |  SJ Earthquakesposition 4 | |
23:00 | position 7Atlético Mineiro | Home win (favourite), market odds: 1.45 | Atlético Mineiro vs Ceará: 0FTFinished0HT 0–0 | Away win (outsider), market odds: 8.59 |  Ceará | |
| 23:00 | position 4Fluminense | Home win (favourite), market odds: 1.66 | Fluminense vs América Mineiro: 0FTFinished2HT 0–2 | Away win (outsider), market odds: 5.61 |  América Mineiro | |
| 23:00 | position 12Coritiba | Home win (favourite), market odds: 2.56 | Coritiba vs RB Bragantino: 2FTFinished1HT 1–1 | Away win (outsider), market odds: 3.09 |  RB Bragantinoposition 8 | |
23:00 | position 3Independiente | Home win (favourite), market odds: 1.89 | Independiente vs Herrera: 2FTFinished3HT 2–1 | Away win (outsider), market odds: 4.33 |  Herreraposition 5 | |
23:00 | position 7Puntarenas | Home win (favourite), market odds: 2.56 | Puntarenas vs Herediano: 0FTFinished0HT 0–0 | Away win (outsider), market odds: 2.86 |  Heredianoposition 8 | |
23:00 | position 5Boca Juniors | Home win (favourite), market odds: 1.40 | Boca Juniors vs Aldosivi: 2FTFinished1HT 2–1 | Away win (outsider), market odds: 9.44 |  Aldosiviposition 9 | |
23:00 | position 11Birmingham Legion | Home win (favourite), market odds: 2.02 | Birmingham Legion vs San Antonio: 1FTFinished2HT 1–1 | Away win (outsider), market odds: 3.36 |  San Antonioposition 6 | |
| 23:00 | position 2Sacramento Republic | Home win (favourite), market odds: 1.83 | Sacramento Republic vs Pittsburgh Riverhounds: 1FTFinished1HT 0–0 | Away win (outsider), market odds: 4.33 |  Pittsburgh Riverhoundsposition 5 | |
23:00 | Central Norte | Home win (favourite), market odds: 1.25 | Central Norte vs Douglas Haig: 1FTFinished1HT 0–1 | Away win (outsider), market odds: 9.03 |  Douglas Haigposition 5 | |
23:00 | Atlante | Home win (favourite), market odds: 1.50 | Atlante vs Tapatío: 4FTFinished1HT 3–0 | Away win (outsider), market odds: 7.39 |  Tapatíoposition 11 | |
23:00 | position 7Olancho | Home win (favourite), market odds: 1.76 | Olancho vs Honduras Progreso: 2FTFinished1HT 1–1 | Away win (outsider), market odds: 3.75 |  Honduras Progreso | |
23:00 | Real de Arteaga | Home win (outsider), market odds: 9.42 | Real de Arteaga vs Cafetaleros de Chiapas: 0FTFinished1HT 0–1 | Away win (favourite), market odds: 1.26 |  Cafetaleros de Chiapas | |
23:00 | San Pedro | —No pre-match price | San Pedro vs Marquense: 2FTFinished0 | —No pre-match price |  Marquense | |
23:00 | Platense | Home win (outsider), market odds: 3.39 | Platense vs Águila: 2FTFinished1HT 0–0 | Away win (favourite), market odds: 2.56 |  Águilaposition 4 | |
23:00 | Deportivo Lara | Home win (favourite), market odds: 2.01 | Deportivo Lara vs Portuguesa: 1FTFinished0HT 0–0 | Away win (outsider), market odds: 3.39 |  Portuguesaposition 2 | |
23:00 | Dandy Town Hornets | —No pre-match price | Dandy Town Hornets vs Boulevard Blazers: 3FTFinished0 | —No pre-match price |  Boulevard Blazers | |
| 23:15 | position 2FAS | Home win (favourite), market odds: 1.44 | FAS vs Santa Tecla: 1FTFinished1HT 1–0 | Away win (outsider), market odds: 8.40 |  Santa Tecla | |
23:15 | position 8Guabirá | Home win (favourite), market odds: 2.40 | Guabirá vs Oriente Petrolero: 2FTFinished1HT 0–1 | Away win (outsider), market odds: 2.86 |  Oriente Petroleroposition 4 | |
23:30 | position 13Puebla | Home win (favourite), market odds: 2.74 | Puebla vs Guadalajara: 1PenAfter Pen.1HT 0–0 | Away win (outsider), market odds: 2.89 |  Guadalajaraposition 3 | |
| 23:45 | Juventud Pinulteca | —No pre-match price | Juventud Pinulteca vs Aurora: 2FTFinished0 | —No pre-match price |  Aurora | |
