23:00 | position 2América de Cali | Home win (favourite), market odds: 1.63 | América de Cali vs Jaguares de Córdoba: 0FTFinished0HT 0–0 | Away win (outsider), market odds: 6.35 |  Jaguares de Córdobaposition 19 | |
23:00 | Deportivo del Este | Home win (outsider), market odds: 3.05 | Deportivo del Este vs Sporting San Miguelito: 1FTFinished2HT 1–1 | Away win (favourite), market odds: 2.33 |  Sporting San Miguelitoposition 5 | |
23:00 | Audax Angra | Home win (outsider), market odds: 6.07 | Audax Angra vs Botafogo: 1FTFinished2HT 1–0 | Away win (favourite), market odds: 1.63 |  Botafogo | |
23:00 | Inter Moengotapoe | —No pre-match price | Inter Moengotapoe vs Voorwaarts: 1FTFinished2 | —No pre-match price |  Voorwaarts | |
23:00 | Llaneros | —No pre-match price | Llaneros vs Millonarios: 2FTFinished1HT 2–1 | —No pre-match price |  Millonarios | |
23:00 | Atlético Marte | Home win (outsider), market odds: 6.06 | Atlético Marte vs Alianza: 1FTFinished0HT 1–0 | Away win (favourite), market odds: 1.57 |  Alianzaposition 7 | |
23:00 | position 4UCV | Home win (outsider), market odds: 2.90 | UCV vs Angostura: 1FTFinished2HT 1–2 | Away win (favourite), market odds: 2.72 |  Angostura | |
23:00 | San Pedro | —No pre-match price | San Pedro vs Sololá: 1FTFinished0 | —No pre-match price |  Sololá | |
| 23:15 | Dragón | Home win (outsider), market odds: 3.04 | Dragón vs Águila: 0FTFinished2HT 0–2 | Away win (favourite), market odds: 2.61 |  Águilaposition 4 | |
| 23:15 | position 1Firpo | Home win (favourite), market odds: 2.05 | Firpo vs Chalatenango: 0FTFinished1HT 0–0 | Away win (outsider), market odds: 3.96 |  Chalatenango | |
23:30 | position 6Libertad | Home win (favourite), market odds: 2.65 | Libertad vs Cerro Porteño: 5FTFinished0HT 5–0 | Away win (outsider), market odds: 2.91 |  Cerro Porteñoposition 3 | |
23:30 | Cumbayá | Home win (outsider), market odds: 4.50 | Cumbayá vs El Nacional: 2FTFinished0HT 2–0 | Away win (favourite), market odds: 1.88 |  El Nacional | |
23:30 | Real Sociedad | Home win (outsider), market odds: 3.03 | Real Sociedad vs Vida: 1FTFinished0HT 0–0 | Away win (favourite), market odds: 2.15 |  Vida | |
23:30 | position 14Racing Córdoba | Home win (favourite), market odds: 2.15 | Racing Córdoba vs Chaco For Ever: 2FTFinished0HT 1–0 | Away win (outsider), market odds: 4.24 |  Chaco For Everposition 9 | |
23:30 | position 11Orlando Pride | Home win (outsider), market odds: 2.75 | Orlando Pride vs Angel City: 1FTFinished2HT 0–1 | Away win (favourite), market odds: 2.19 |  Angel Cityposition 5 | |
23:30 | position 4Cerrito | —No pre-match price | Cerrito vs Miramar Misiones: 2FTFinished2HT 1–0 | —No pre-match price |  Miramar Misiones | |
23:30 | Progresso | —No pre-match price | Progresso vs Internacional Belmopan: 2FTFinished0 | —No pre-match price |  Internacional Belmopan | |
23:30 | Venezuela U17 | —No pre-match price | Venezuela U17 vs Paraguay U17: 1FTFinished1HT 0–0 | —No pre-match price |  Paraguay U17 | |
| 23:45 | position 2Ferro Carril Oeste | Home win (favourite), market odds: 2.10 | Ferro Carril Oeste vs Deportivo Maipú: 0FTFinished1HT 0–1 | Away win (outsider), market odds: 4.15 |  Deportivo Maipúposition 6 | |
