01:00 | position 7León | Home win (favourite), market odds: 1.89 | León vs Querétaro: 0FTFinished2HT 0–1 | Away win (outsider), market odds: 4.17 |  Querétaroposition 12 | |
01:00 | Santos de Guápiles | Home win (outsider), market odds: 3.32 | Santos de Guápiles vs Municipal Liberia: 3FTFinished0HT 1–0 | Away win (favourite), market odds: 2.20 |  Municipal Liberia | |
| 01:00 | position 2Cartaginés | Home win (outsider), market odds: 3.89 | Cartaginés vs Alajuelense: 0FTFinished0HT 0–0 | Away win (favourite), market odds: 1.87 |  Alajuelenseposition 4 | |
01:00 | position 5Everton | Home win (favourite), market odds: 1.95 | Everton vs Audax Italiano: 2FTFinished0HT 0–0 | Away win (outsider), market odds: 4.05 |  Audax Italianoposition 13 | |
01:00 | position 6Barcelona | Home win (favourite), market odds: 1.53 | Barcelona vs Deportivo Cuenca: 4FTFinished0HT 2–0 | Away win (outsider), market odds: 5.67 |  Deportivo Cuencaposition 11 | |
01:00 | Sporting Canamy | Home win (outsider), market odds: 4.00 | Sporting Canamy vs Escorpiones: 2PenAfter Pen.2HT 0–0 | Away win (favourite), market odds: 1.73 |  Escorpiones | |
| 01:00 | UA Zacatecas | Home win (favourite), market odds: 1.77 | UA Zacatecas vs Orgullo Reynosa: 2PenAfter Pen.2HT 0–0 | Away win (outsider), market odds: 4.05 |  Orgullo Reynosa | |
| 01:00 | Mexicali FC | Home win (outsider), market odds: 4.00 | Mexicali FC vs Mineros de Fresnillo: 1FTFinished0HT 1–0 | Away win (favourite), market odds: 1.80 |  Mineros de Fresnilloposition 4 | |
01:00 | Santana | Home win (favourite), market odds: 1.83 | Santana vs São Paulo AP: 7FTFinished1 | Away win (outsider), market odds: 3.00 |  São Paulo AP | |
01:00 | position 15Greenville Triumph | Home win (favourite), market odds: 2.30 | Greenville Triumph vs Northern Colorado: 3FTFinished1HT 1–0 | Away win (outsider), market odds: 2.70 |  Northern Colorado | |
01:00 | position 5Pittsburgh Riverhounds | Home win (favourite), market odds: 2.25 | Pittsburgh Riverhounds vs Tampa Bay Rowdies: 0FTFinished0HT 0–0 | Away win (outsider), market odds: 3.20 |  Tampa Bay Rowdiesposition 1 | |
01:00 | Independência | Home win (outsider), market odds: 2.80 | Independência vs Rio Branco: 2FTFinished2HT 1–1 | Away win (favourite), market odds: 2.00 |  Rio Branco | |
01:00 | position 6UPNFM | Home win (outsider), market odds: 2.94 | UPNFM vs Olancho: 0FTFinished1HT 0–1 | Away win (favourite), market odds: 2.32 |  Olanchoposition 7 | |
01:00 | União Cacoalense | —No pre-match price | União Cacoalense vs Porto Velho EC: 0FTFinished1HT 0–0 | —No pre-match price |  Porto Velho EC | |
01:00 | Michigan Stars | Home win (favourite), market odds: 1.55 | Michigan Stars vs Savannah Clovers: 3FTFinished2HT 1–0 | Away win (outsider), market odds: 5.25 |  Savannah Clovers | |
01:00 | position 4Cerrito | —No pre-match price | Cerrito vs Cooper: 1FTFinished1HT 1–0 | —No pre-match price |  Cooper | |
01:00 | position 1Managua | Home win (favourite), market odds: 1.62 | Managua vs Sport Sébaco: 1FTFinished1HT 0–0 | Away win (outsider), market odds: 4.75 |  Sport Sébacoposition 6 | |
01:00 | Voorwaarts | —No pre-match price | Voorwaarts vs Transvaal: 0FTFinished1HT 0–0 | —No pre-match price |  Transvaal | |
01:00 | Ellerton | —No pre-match price | Ellerton vs Kick Start: 0FTFinished2 | —No pre-match price |  Kick Start | |
01:10 | position 4Atlético Bucaramanga | Home win (favourite), market odds: 1.99 | Atlético Bucaramanga vs Deportivo Cali: 2FTFinished1HT 1–0 | Away win (outsider), market odds: 4.37 |  Deportivo Caliposition 3 | |
01:10 | Independiente Medellín | —No pre-match price | Independiente Medellín vs América de Cali: 2FTFinished3HT 2–0 | —No pre-match price |  América de Cali | |
01:15 | position 4Universitario | Home win (outsider), market odds: 3.60 | Universitario vs Plaza Amador: 0FTFinished4HT 0–2 | Away win (favourite), market odds: 1.91 |  Plaza Amadorposition 1 | |
01:30 | position 1Vancouver Whitecaps | Home win (favourite), market odds: 1.54 | Vancouver Whitecaps vs Toronto: 4FTFinished0HT 2–0 | Away win (outsider), market odds: 6.42 |  Torontoposition 12 | |
| 01:30 | position 9Cincinnati | Home win (favourite), market odds: 2.25 | Cincinnati vs New York RB: 1FTFinished2HT 1–1 | Away win (outsider), market odds: 3.46 |  New York RBposition 10 | |
| 01:30 | position 7Columbus Crew | Home win (favourite), market odds: 1.62 | Columbus Crew vs D.C. United: 1FTFinished1HT 0–0 | Away win (outsider), market odds: 5.30 |  D.C. Unitedposition 14 | |
| 01:30 | position 2Inter Miami | Home win (favourite), market odds: 2.32 | Inter Miami vs Colorado Rapids: 2FTFinished2HT 0–1 | Away win (outsider), market odds: 3.06 |  Colorado Rapidsposition 12 | |
| 01:30 | position 3New England | Home win (favourite), market odds: 2.32 | New England vs Charlotte: 1FTFinished0HT 1–0 | Away win (outsider), market odds: 3.20 |  Charlotteposition 5 | |
| 01:30 | position 11New York City | Home win (favourite), market odds: 2.07 | New York City vs Atlanta United: 1FTFinished1HT 1–0 | Away win (outsider), market odds: 3.62 |  Atlanta Unitedposition 13 | |
| 01:30 | Tormenta | Home win (favourite), market odds: 2.38 | Tormenta vs Lexington: 3FTFinished0HT 2–0 | Away win (outsider), market odds: 2.57 |  Lexington | |
| 01:30 | position 7Rhode Island | Home win (outsider), market odds: 3.70 | Rhode Island vs Charleston Battery: 0FTFinished0HT 0–0 | Away win (favourite), market odds: 1.85 |  Charleston Batteryposition 2 | |
| 01:30 | City Torque | —No pre-match price | City Torque vs Colón: 3FTFinished0HT 0–0 | —No pre-match price |  Colónposition 3 | |
| 01:45 | position 6Los Angeles | Home win (favourite), market odds: 1.78 | Los Angeles vs LA Galaxy: 2FTFinished1HT 2–1 | Away win (outsider), market odds: 4.18 |  LA Galaxyposition 11 | |
