01:00 | position 2Nacional Asuncion | Home win (favourite), market odds: 2.19 | Nacional Asuncion vs Sportivo Trinidense: 2FTFinished1HT 0–1 | Away win (outsider), market odds: 3.63 |  Sportivo Trinidenseposition 5 | |
01:00 | position 15Greenville | —No pre-match price | Greenville vs Richmond Kickers: 0FTFinished3HT 0–1 | —No pre-match price |  Richmond Kickersposition 17 | |
01:00 | position 12Brooklyn | Home win (favourite), market odds: 2.39 | Brooklyn vs Loudoun: 0FTFinished1HT 0–1 | Away win (outsider), market odds: 2.72 |  Loudounposition 10 | |
| 01:00 | position 6Hartford Athletic | Home win (favourite), market odds: 2.54 | Hartford Athletic vs Detroit: 2FTFinished1HT 0–0 | Away win (outsider), market odds: 2.88 |  Detroitposition 3 | |
| 01:00 | position 9Indy Eleven | Home win (favourite), market odds: 1.64 | Indy Eleven vs Sporting Jax: 2FTFinished1HT 0–1 | Away win (outsider), market odds: 5.20 |  Sporting Jaxposition 13 | |
| 01:00 | position 4Louisville City | Home win (favourite), market odds: 1.45 | Louisville City vs Pittsburgh: 0FTFinished2HT 0–1 | Away win (outsider), market odds: 7.02 |  Pittsburghposition 5 | |
01:00 | Virginia Beach | —No pre-match price | Virginia Beach vs Lionsbridge: 1FTFinished1HT 1–1 | —No pre-match price |  Lionsbridge | |
01:00 | Cacerense | —No pre-match price | Cacerense vs Atletico MT: 3FTFinished0HT 1–0 | —No pre-match price |  Atletico MT | |
01:00 | Pacific FC | —No pre-match price | Pacific FC vs Cavalry: 1FTFinished3HT 0–1 | —No pre-match price |  Cavalry | |
01:10 | position 11Deportes Tolima | Home win (favourite), market odds: 1.80 | Deportes Tolima vs Dep. Pasto: 1FTFinished0HT 1–0 | Away win (outsider), market odds: 4.76 |  Dep. Pastoposition 18 | |
01:30 | position 13Atlanta Utd | Home win (favourite), market odds: 2.37 | Atlanta Utd vs Los Angeles Galaxy: 1FTFinished2HT 0–0 | Away win (outsider), market odds: 2.97 |  Los Angeles Galaxyposition 7 | |
| 01:30 | position 5Charlotte | Home win (favourite), market odds: 2.22 | Charlotte vs FC Cincinnati: 2FTFinished2HT 0–2 | Away win (outsider), market odds: 3.09 |  FC Cincinnatiposition 7 | |
| 01:30 | position 3New England Revolution | Home win (favourite), market odds: 2.61 | New England Revolution vs Philadelphia Union: 2FTFinished1HT 0–1 | Away win (outsider), market odds: 2.74 |  Philadelphia Unionposition 6 | |
01:30 | position 6CRB | Home win (favourite), market odds: 2.12 | CRB vs Operario-PR: 3FTFinished0HT 2–0 | Away win (outsider), market odds: 3.64 |  Operario-PRposition 10 | |
01:30 | Tampa Bay Sun W | —No pre-match price | Tampa Bay Sun W vs Dallas Trinity W: 0FTFinished2HT 0–2 | —No pre-match price |  Dallas Trinity W | |
| 01:30 | Fort Lauderdale W | —No pre-match price | Fort Lauderdale W vs Carolina Ascent W: 0FTFinished3HT 0–0 | —No pre-match price |  Carolina Ascent W | |
| 01:30 | position 9Fort Wayne | —No pre-match price | Fort Wayne vs Westchester SC: 1FTFinished0HT 1–0 | —No pre-match price |  Westchester SCposition 10 | |
| 01:30 | position 7Rhode Island | Home win (favourite), market odds: 2.46 | Rhode Island vs Tampa Bay: 1FTFinished1HT 0–1 | Away win (outsider), market odds: 2.99 |  Tampa Bayposition 1 | |
| 01:30 | Apotheos | —No pre-match price | Apotheos vs Columbus United: 1FTFinished2HT 0–0 | —No pre-match price |  Columbus United | |
01:30 | position 5Defensores de Vilelas | —No pre-match price | Defensores de Vilelas vs Bartolome Mitre: 1FTFinished3HT 1–1 | —No pre-match price |  Bartolome Mitreposition 7 | |
01:30 | Guapore | —No pre-match price | Guapore vs Galvez: 1FTFinished0HT 0–0 | —No pre-match price |  Galvez | |
01:30 | position 13Tomayapo | Home win (favourite), market odds: 2.30 | Tomayapo vs SA Bulo Bulo: 1FTFinished0HT 0–0 | Away win (outsider), market odds: 2.60 |  SA Bulo Buloposition 12 | |
Lambton J.
