| 16:00 | Tobol | Home win (favourite), market odds: 1.83 | Tobol vs Derry City: 1FTFinished0HT 0–0 | Away win (outsider), market odds: 4.65 | Derry City | LLWWDDWWWD | 2.0 avg from 20 matches | 10.1 avg from 11 matches | 5.4 avg from 19 matches | |
| 17:00 | Struga | Home win (outsider), market odds: 3.25 | Struga vs Swift Hesperange: 3FTFinished1HT 2–0 | Away win (favourite), market odds: 2.34 | Swift Hesperange | WWWLDWWDWL | 3.1 avg from 20 matches | 8.0 avg from 9 matches | 4.4 avg from 14 matches | |
| 18:00 | Bodø / Glimt | Home win (favourite), market odds: 1.22 | Bodø / Glimt vs Pyunik: 3FTFinished0HT 2–0 | Away win (outsider), market odds: 12.56 | Pyunik | LWLWWDWWWW | 3.4 avg from 20 matches | 9.8 avg from 11 matches | 3.7 avg from 19 matches | |
| 18:00 | Sabah | Home win (outsider), market odds: 2.76 | Sabah vs Partizan: 2FTFinished0HT 0–0 | Away win (favourite), market odds: 2.72 | Partizan | WWWDWWDDLW | 3.0 avg from 20 matches | 8.3 avg from 7 matches | 3.9 avg from 14 matches | |
| 19:00 | Valmiera | Home win (outsider), market odds: 3.48 | Valmiera vs Partizani Tirana: 1FTFinished2HT 1–0 | Away win (favourite), market odds: 2.16 | Partizani Tirana | WWWLLWWLDW | 2.9 avg from 20 matches | 7.5 avg from 8 matches | 3.9 avg from 17 matches | |
| 19:00 | FC Santa Coloma | Home win (outsider), market odds: 28.23 | FC Santa Coloma vs AZ: 0FTFinished1HT 0–0 | Away win (favourite), market odds: 1.10 | AZ | WLDDLWWWDW | 2.8 avg from 20 matches | 8.7 avg from 11 matches | 3.9 avg from 13 matches | |
| 19:00 | Dila | Home win (outsider), market odds: 3.75 | Dila vs APOEL: 0FTFinished2HT 0–1 | Away win (favourite), market odds: 2.29 | APOEL | WLWLDWWDWL | 2.9 avg from 20 matches | 10.6 avg from 9 matches | 4.8 avg from 16 matches | |
| 19:00 | Legia Warsaw | Home win (favourite), market odds: 1.78 | Legia Warsaw vs Austria Vienna: 1FTFinished2HT 0–1 | Away win (outsider), market odds: 4.26 | Austria Vienna | WWDWDWWLWW | 3.3 avg from 20 matches | 10.9 avg from 13 matches | 4.5 avg from 13 matches | |
| 19:00 | Viktoria Plzen | Home win (favourite), market odds: 1.06 | Viktoria Plzen vs Gzira United: 4FTFinished0HT 2–0 | Away win (outsider), market odds: 39.27 | Gzira United | WWDDLLWDDW | 3.5 avg from 20 matches | 11.5 avg from 8 matches | 5.3 avg from 16 matches | |
| 19:00 | Rosenborg | Home win (favourite), market odds: 1.95 | Rosenborg vs Hearts: 2FTFinished1HT 2–0 | Away win (outsider), market odds: 4.11 | Heartsposition 32 | WDWDWWLLWW | 2.7 avg from 20 matches | 10.8 avg from 13 matches | 5.0 avg from 14 matches | |
| 19:00 | Sepsi | Home win (favourite), market odds: 1.65 | Sepsi vs Aktobe: 1FTFinished1HT 0–0 | Away win (outsider), market odds: 5.77 | Aktobe | DWWWWWLDWW | 2.5 avg from 20 matches | 8.3 avg from 8 matches | 6.4 avg from 17 matches | |
| 19:00 | Neftchi Baku | Home win (outsider), market odds: 6.02 | Neftchi Baku vs Besiktas: 1FTFinished3HT 0–2 | Away win (favourite), market odds: 1.60 | Besiktas | LWDLLWWWWD | 3.3 avg from 20 matches | 9.5 avg from 10 matches | 3.7 avg from 16 matches | |
| 19:00 | Omonia Nicosia | Home win (outsider), market odds: 3.22 | Omonia Nicosia vs Midtjylland: 1FTFinished0HT 1–0 | Away win (favourite), market odds: 2.45 | Midtjyllandposition 34 | WWLWWLLWWW | 3.1 avg from 20 matches | 8.8 avg from 12 matches | 3.3 avg from 16 matches | |
| 19:30 | FCV Farul Constanţa | Home win (favourite), market odds: 1.39 | FCV Farul Constanţa vs Flora: 3FTFinished0HT 0–0 | Away win (outsider), market odds: 7.70 | Flora | LWLWWWLDLD | 3.0 avg from 20 matches | 10.2 avg from 11 matches | 3.8 avg from 16 matches | |
| 19:30 | Hamrun Spartans | Home win (outsider), market odds: 5.41 | Hamrun Spartans vs Ferencváros: 1FTFinished6HT 0–1 | Away win (favourite), market odds: 1.55 | Ferencváros | WWLLWWWWLD | 3.2 avg from 20 matches | 9.2 avg from 10 matches | 3.4 avg from 16 matches | |
| 19:30 | Hapoel Be'er Sheva | Home win (favourite), market odds: 1.93 | Hapoel Be'er Sheva vs Levski Sofia: 0FTFinished0HT 0–0 | Away win (outsider), market odds: 4.64 | Levski Sofia | DWLDLLWWWW | 2.7 avg from 20 matches | 8.5 avg from 11 matches | 3.6 avg from 15 matches | |
| 20:00 | Arouca | Home win (favourite), market odds: 2.54 | Arouca vs Brann: 2FTFinished1HT 1–0 | Away win (outsider), market odds: 2.78 | Brannposition 6 | DWWWDWLLWL | 2.6 avg from 20 matches | 10.9 avg from 12 matches | 3.0 avg from 15 matches | |
| 20:00 | Adana Demirspor | Home win (favourite), market odds: 1.53 | Adana Demirspor vs Osijek: 5FTFinished1HT 2–0 | Away win (outsider), market odds: 5.82 | Osijek | WDLWWWWWWL | 4.0 avg from 20 matches | 11.1 avg from 13 matches | 4.6 avg from 13 matches | |
| 20:00 | B36 | Home win (outsider), market odds: 7.53 | B36 vs Rijeka: 1FTFinished3HT 1–1 | Away win (favourite), market odds: 1.47 | Rijeka | DLWDDWWLWW | 2.6 avg from 20 matches | 9.2 avg from 9 matches | 4.3 avg from 18 matches | |
| 20:00 | Celje | Home win (favourite), market odds: 1.72 | Celje vs Neman Grodno: 1FTFinished0HT 0–0 | Away win (outsider), market odds: 5.21 | Neman Grodno | WWLDDDWDWW | 3.0 avg from 20 matches | 10.2 avg from 11 matches | 3.8 avg from 12 matches | |
| 20:00 | Club Brugge | Home win (favourite), market odds: 1.02 | Club Brugge vs KA: 5FTFinished1HT 4–0 | Away win (outsider), market odds: 49.84 | KA | WLDWLLDDWW | 2.9 avg from 20 matches | 8.7 avg from 11 matches | 4.1 avg from 17 matches | |
| 20:00 | Fenerbahce | Home win (favourite), market odds: 1.18 | Fenerbahce vs Maribor: 3FTFinished1HT 0–0 | Away win (outsider), market odds: 14.48 | Maribor | WWWLDDWDWW | 3.0 avg from 20 matches | 10.4 avg from 13 matches | 4.5 avg from 17 matches | |
| 20:00 | Lech Poznań | Home win (favourite), market odds: 1.46 | Lech Poznań vs Spartak Trnava: 2FTFinished1HT 0–0 | Away win (outsider), market odds: 7.69 | Spartak Trnava | DWWWWDWLDL | 2.9 avg from 20 matches | 9.5 avg from 15 matches | 4.2 avg from 13 matches | |
| 20:00 | position 3Twente | Home win (favourite), market odds: 1.33 | Twente vs Riga: 2FTFinished0HT 1–0 | Away win (outsider), market odds: 9.18 | Rigaposition 19 | LWDWWWWWLW | 3.5 avg from 20 matches | 11.2 avg from 11 matches | 4.0 avg from 17 matches | |
| 20:15 | Aris | Home win (outsider), market odds: 3.14 | Aris vs Dinamo Kiev: 1FTFinished0HT 0–0 | Away win (favourite), market odds: 2.37 | Dinamo Kiev | WDLLWWWWWW | 3.7 avg from 20 matches | 9.4 avg from 11 matches | 4.8 avg from 13 matches | |
| 20:30 | FCSB | Home win (outsider), market odds: 2.86 | FCSB vs Nordsjælland: 0FTFinished0HT 0–0 | Away win (favourite), market odds: 2.50 | Nordsjællandposition 25 | WWWWWWWWLD | 3.3 avg from 20 matches | 7.6 avg from 16 matches | 3.8 avg from 15 matches | |
| 20:30 | Hibernian | Home win (outsider), market odds: 2.84 | Hibernian vs Luzern: 3FTFinished1HT 0–0 | Away win (favourite), market odds: 2.44 | Luzern | LWLLWLDWWD | 3.3 avg from 20 matches | 10.4 avg from 13 matches | 5.1 avg from 12 matches | |
| 20:45 | Ballkani | Home win (favourite), market odds: 1.25 | Ballkani vs Lincoln Red Imps: 2FTFinished0HT 0–0 | Away win (outsider), market odds: 11.88 | Lincoln Red Impsposition 22 | WWLWDWLLDL | 2.9 avg from 20 matches | 10.3 avg from 7 matches | 3.1 avg from 9 matches | |
| 21:00 | Rapid Vienna | Home win (favourite), market odds: 1.47 | Rapid Vienna vs Debrecen: 0FTFinished0HT 0–0 | Away win (outsider), market odds: 6.71 | Debrecen | WDWLLLWWLW | 3.7 avg from 20 matches | 10.1 avg from 7 matches | 4.2 avg from 9 matches | |
| 21:00 | position 13Hajduk Split | Home win (favourite), market odds: 2.09 | Hajduk Split vs PAOK: 0FTFinished0HT 0–0 | Away win (outsider), market odds: 3.92 | PAOK | WWLWDWDLWW | 2.6 avg from 20 matches | 6.9 avg from 8 matches | 3.3 avg from 10 matches | |