21:00 | Ajax | Home win (favourite), market odds: 1.31 | Ajax vs Maccabi Tel Aviv: 5FTFinished0HT 3–0 | Away win (outsider), market odds: 9.53 |  Maccabi Tel Aviv | WWWWWLLLWW | 2.9 avg from 20 matches | 8.4 avg from 16 matches | 5.2 avg from 20 matches | |
| 21:00 | position 14AZ | Home win (outsider), market odds: 2.94 | AZ vs Fenerbahce: 3FTFinished1HT 0–0 | Away win (favourite), market odds: 2.51 |  Fenerbahce | LDLLLWWDDD | 3.3 avg from 20 matches | 9.5 avg from 18 matches | 5.1 avg from 18 matches | |
| 21:00 | Dinamo Kiev | Home win (favourite), market odds: 2.45 | Dinamo Kiev vs Ferencváros: 0FTFinished4HT 0–0 | Away win (outsider), market odds: 3.12 |  Ferencvárosposition 3 | WDDLWDWDWW | 2.9 avg from 20 matches | 8.9 avg from 11 matches | 3.4 avg from 20 matches | |
| 21:00 | Lazio | Home win (favourite), market odds: 2.46 | Lazio vs Porto: 2FTFinished1HT 1–0 | Away win (outsider), market odds: 3.09 |  Porto | WWWWLWWWWW | 3.5 avg from 20 matches | 9.4 avg from 16 matches | 4.9 avg from 20 matches | |
| 21:00 | Manchester United | Home win (favourite), market odds: 1.24 | Manchester United vs PAOK: 2FTFinished0HT 0–0 | Away win (outsider), market odds: 11.43 |  PAOK | DWLDWWWLDD | 2.8 avg from 20 matches | 10.1 avg from 18 matches | 4.7 avg from 19 matches | |
| 21:00 | Rigas FS | Home win (outsider), market odds: 4.65 | Rigas FS vs Anderlecht: 1FTFinished1HT 0–0 | Away win (favourite), market odds: 1.74 |  Anderlechtposition 15 | WDWLWWWLWL | 3.0 avg from 20 matches | 10.5 avg from 11 matches | 4.7 avg from 18 matches | |
| 21:00 | position 23Hoffenheim | Home win (outsider), market odds: 2.82 | Hoffenheim vs Lyon: 2FTFinished2HT 0–0 | Away win (favourite), market odds: 2.40 |  Lyonposition 13 | LWDLWDDLWW | 2.8 avg from 20 matches | 11.0 avg from 18 matches | 4.1 avg from 18 matches | |
| 21:00 | position 30Viktoria Plzen | Home win (outsider), market odds: 4.18 | Viktoria Plzen vs Real Sociedad: 2FTFinished1HT 1–1 | Away win (favourite), market odds: 1.99 |  Real Sociedadposition 20 | LWWDWWLWWD | 2.5 avg from 20 matches | 9.8 avg from 17 matches | 4.0 avg from 17 matches | |
21:00 | APOEL | Home win (outsider), market odds: 5.84 | APOEL vs Fiorentina: 2FTFinished1HT 2–0 | Away win (favourite), market odds: 1.62 |  Fiorentina | DWLWLWWWWW | 2.6 avg from 20 matches | 7.6 avg from 11 matches | 5.1 avg from 20 matches | |
| 21:00 | Chelsea | Home win (favourite), market odds: 1.04 | Chelsea vs Noah: 8FTFinished0HT 6–0 | Away win (outsider), market odds: 41.28 |  Noah | DLWWLWWLWW | 3.3 avg from 20 matches | 11.0 avg from 12 matches | 5.3 avg from 15 matches | |
| 21:00 | Djurgården | Home win (outsider), market odds: 3.55 | Djurgården vs Panathinaikos: 2FTFinished1HT 0–1 | Away win (favourite), market odds: 2.16 |  Panathinaikosposition 2 | LWLLWWDLWD | 2.5 avg from 20 matches | 9.4 avg from 19 matches | 4.5 avg from 19 matches | |
| 21:00 | position 7FC Copenhagen | Home win (favourite), market odds: 1.52 | FC Copenhagen vs Istanbul Basaksehir: 2FTFinished2HT 0–1 | Away win (outsider), market odds: 6.59 |  Istanbul Basaksehir | DWDDWLDLLD | 3.0 avg from 20 matches | 8.0 avg from 16 matches | 4.0 avg from 20 matches | |
| 21:00 | position 32Hearts | Home win (outsider), market odds: 3.08 | Hearts vs Heidenheim: 0FTFinished2HT 0–0 | Away win (favourite), market odds: 2.36 |  Heidenheim | WLDWWLLDWL | 2.7 avg from 20 matches | 9.3 avg from 19 matches | 4.8 avg from 19 matches | |
| 21:00 | Jagiellonia Białystok | Home win (outsider), market odds: 3.07 | Jagiellonia Białystok vs Molde: 3FTFinished0HT 1–0 | Away win (favourite), market odds: 2.30 |  Molde | WWWWWDWLLW | 3.4 avg from 20 matches | 7.3 avg from 16 matches | 3.3 avg from 17 matches | |
| 21:00 | Larne | Home win (outsider), market odds: 7.02 | Larne vs St.Gallen: 1FTFinished2HT 1–1 | Away win (favourite), market odds: 1.42 |  St.Gallen | WLLDLDDDLL | 3.5 avg from 20 matches | 9.3 avg from 12 matches | 4.2 avg from 19 matches | |
| 21:00 | LASK | Home win (favourite), market odds: 1.98 | LASK vs Cercle Brugge: 0FTFinished0HT 0–0 | Away win (outsider), market odds: 3.89 |  Cercle Brugge | DWLWWWWWLD | 3.1 avg from 20 matches | 9.4 avg from 14 matches | 3.7 avg from 18 matches | |
| 21:00 | Real Betis | Home win (favourite), market odds: 1.23 | Real Betis vs Celje: 2FTFinished1HT 0–0 | Away win (outsider), market odds: 12.49 |  Celje | DWWDWLWLWW | 3.5 avg from 20 matches | 8.9 avg from 11 matches | 5.6 avg from 14 matches | |
| 21:00 | Vitoria Guimaraes | Home win (favourite), market odds: 1.30 | Vitoria Guimaraes vs Mladá Boleslav: 2FTFinished1HT 1–0 | Away win (outsider), market odds: 10.58 |  Mladá Boleslav | WLDWWWWDLD | 2.6 avg from 20 matches | 10.0 avg from 15 matches | 4.1 avg from 19 matches | |
21:00 | position 5West Bromwich Albion | Home win (favourite), market odds: 2.47 | West Bromwich Albion vs Burnley: 0FTFinished0HT 0–0 | Away win (outsider), market odds: 3.20 |  Burnleyposition 22 | DDDDDLDDWD | 1.4 avg from 20 matches | 10.0 avg from 19 matches | 4.6 avg from 19 matches | |
NSeth Berchem
Alianza Beni
Ajoie-Monterri
Sliema Wanderersposition 3
Florianaposition 6
Tuna Luso PA U20
Comoposition 5
Santa Ana
Águilaposition 4
Matagalpa U20
Mictlán
Lanúsposition 2
Millonariosposition 7
Argentinos Juniorsposition 5